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Dolcini Virginia
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| Indirizzo:
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Via Nizza 17/8 |
| Cap:
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16145 |
| Cittŕ:
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Genova |
| Nazione:
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Italia |
| E-mail:
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virginia.dolcini@virgilio.it |
| Telefono:
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+39-010-3620941 |
| Luogo di nascita:
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Genova |
| Data di nascita:
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23/11/1974 |
| Laurea in:
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Scienze Biologiche: indirizzo Bio-Molecolare |
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| Universitŕ:
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Genova |
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| Breve Curriculum vitae:
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EDUCATION
December 2003 Successfully obtained PhD in Neuropharmacology at Advanced Biotechnology Center in Genoa.
May 2000 Qualified as a biologist-(148/150).
Nov. 93-Dec. 98 Master of Biological Science at Univ. of Genoa- Graduated with full marks and honours in Biology- bio-molecular course. Title of Thesis "Biological effets of neurotoxic pharmaceutical products on the early embryonal development of sea urchin".
Part of this project has been carried out in the laboratory of Physiology and Toxicology at the University of Nice-Sophia Antipolis-France with Prof. J.P. Girard as my Senior supervisor.
July 93 Obtained school-leaving certificate awarded after five years of “Liceo” specialising in humanistic studies at the state Liceo “A.D’Oria” of Genoa.
WORK EXPERIENCES
March 05-present PostDoctoral Fellow , Mount Sinai School Medicine, Psychiatry Dept-New York
Jan.04-March. 05 PostDoctoral Fellowship at University College Cork in Ireland at Biochemistry Department, Biosciences Institute. Directed by Dr. J.V. McCarthy.
Dec. 00-Dec. 03 PhD student in Neurophysiology and Neuropharmacology at the Section of Neuroscience, Direct by Prof. G. Schettini c/o Advanced Biotechnology Center (ABC), Genova, Italy.
Dic. 00-Dic. 03 European Doctorate in Biotechnology (EDBT) student, a programme of the European Association for Higher Education in Biotechnology.
Mar.00-Nov.00 Grant at Neuroscience Section, ABC.
Jan.99- Mar.00 Apprenticeship at the Human Anatomy Section of Genoa, Prof. F. Floriani and at the Neuroscience Section, Prof. G. Schettini, ABC.
OTHER EXPERIENCES OF STUDY AND RESEARCH
23 June 2003 Rapporteur of the follow seminary “Interaction between carboxy-terminal fragments of amyloid precursor protein and ShcA/Grb2 adaptors in Alzheimer’s disease and Down’s syndrome human brains” at the invitation of Dr. Davletov Bazbek, Group Leader of the Neurobiology Division at the Medical Research Council-Laboratory of Molecular Biology, Cambridge, UK.
March-April 2003 Attended the “Advanced Course in Biotechnology Ethics”, held at the Abbaye des Vaux de Cernay, Cernay, France ; from March 29 to April 4, 2003; sponsored by the European Commission.
Dec. 2002 Attended the “Tracking Biomolecules into the Cell. 4th Intensive Pratical Workshop on Confocal and Two-photon Microscopy”, at the Department of Physics, Laboratory for Advances Microscopy, Bioimaging and Spectroscopy.
July 2002 Received a Travel Fellowship from the Scientific Program Committee of Alzheimer’s Association in amount of 350$ to partecipate to the 8th Alzheimer’s Disease Conference in Stockolm .
May 2002 Attended the Symposium on "Molecular basis of neurodegenerative diseases" at the University of Nice Sophia-Antipolis-France.
Jan. 2002-present Tutorship of an apprentice in Biological Sciences and coordinator of her research activities.
Nov. 2001 Attended the Advanced Course of Immunohistochemistry feld at the DAKO Industry in Milan.
July.-Sett.2001 Attended the course of economics and managment at the School of Business and Managment (SDA) of the Bocconi University in Milan for 25 days and passed with success the exams at the end of the course.
7-10 Febr.2000 Attended the Biovision, World Life Sciences Forum held at the Lyon Conference Center.
Jan.2000 Rapporteur of the follow seminar :"Role of Shc adaptor proteins in the signal transduction pathway and their interaction with amyloid precursor protein in Alzheimer’s disease" at the Advanced Biotechnology Center.
1999-2002 Carried out studies for the identification of phosphorylated amino-terminal and carboxy-terminal fragments of the amyloid precursor protein in Alzheimer’s disease and Down’s syndrome.
During these years I studied the interaction of ShcA/Grb2 adaptor proteins with C-terminal fragments of the amyloid precursor protein in the human Central Nervous System, both in Alzheimer’s disease brains and in Down’s syndrome brains, and also in fibroblasts cultured cells.
1996-1997 Studied in Erasmus-Socrates program at the Nice-Sophia Antipolis University (France).
1997-1998 Studied the biological and pharmacological effects of neurotoxical products on the early embryonal development of the sea urchin.
1996-1997 Studied toxicological and microtubules-dependent effects of Caulerpenine , a toxin extracted from Caulerpa taxifolia during the first mitotic division of the sea urchin.
May1997 Rapporteur of a seminar in french language : "Effets de la Caulerpenine sur les evenements mitotiques chez les oeufs d’ousin" at the Laboratory of Physiology and Toxicology at the University of Nice-Sophia –Antipolis, France.
Mar.-Giu.97 Stage at the Laboratory of Physiology and Toxicology of Nice with Prof. J.P.Girard as my Senior supervisor.
19-20 Set.97 Third Internatal Workshop on " Caulerpa taxifolia " in Marseille organized by CEE-LIFE-Caulerpa DG XI.
REFERENCES
- Dr. J.V. McCarthy, Director of Signal Transduction Laboratory at Biochemistry Department, Biosciences Institute, University College Cork, Ireland.
Phone: 00353214901374 E-Mail: jv.mccarthy@ucc.ie
- Prof. G.B. Ferrara, Full Professor in Molecular Biology and Head of Department Immunogenetics Lab.-Genoa University-
Phone: +39-010-5737236 E-mail: ferrara@cba.unige.it
- Prof. G.C. Schito, Full Professor of Clinical Microbiology at Genoa University-
Phone: +39-010-3537646 E-mail: microbiologia@unige.it
- Prof. F. Celada, Full Professor and Secretary General og European Doctorate in Biotechnology, Genoa University-
Phone:+39-010-5737303 E-mail: celada@cba.unige.it
- Prof. J.P. Girard (reference in french language-written at the end on my Erasmus stage) Professor and Director of Experimental Physiology and Toxicology, University of Nice-Sophia Antipolis-
Phone: +33-0492076896
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| Lingue conosciute:
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Inglese = Ottimo; Francese = Ottimo; |
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| Sede di lavoro:
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New York |
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| Posizione attuale:
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PostDoctoral Fellow |
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Titoli completi dei 5 lavori
piů significativi negli ultimi
3-5 anni:
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Venezia V, Russo C, Repetto E, Salis S, Dolcini V, Genova F, Nizzari M, Mueller U, Schettini G.
Apoptotic cell death influences the signaling activity of the amyloid precursor protein through ShcA and Grb2 adaptor proteins in neuroblastoma SH-SY5Y cells.
J Neurochem. 2004 Sep;90(6):1359-70.
D. Pesando, P. Huitorel, V. Dolcini, C. Angelini, P. Guidetti, C. Falugi : Biological targets of neurotoxic pesticides analysed by alteration of developmental events in the Mediterrean Sea Urchin, Paracentrotus lividus. Mar. Environ. Res. 2003, Feb; 55(1):39-57. Impact Factor :1,200.
Russo C.; Dolcini V.; Salis S.; Venezia V.; Violani E.; Carlo P.; Zambrano N.; Russo T.; Schettini G. : Signal trasduction through tyrosyne-phosphorylated carboxy-terminal fragments of APP via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer’s disease brain. Ann. N Y Acad. Sci. 2002, Nov;973:323-333. Impact Factor :1,381.
C. Russo, V. Dolcini, S. Salis, V. Venezia, I. Decherchi, N. Zambrano, T. Russo, G. Schettini : Signal transduction through tyrosine phosphorylated carboxy-terminal fragments of amyloid precursor protein in Alzheimer’s disease brain. J Biol Chem 2002 Sep 20; 277(38): 35282-8 . Impact Factor :7,368.
C. Russo, E. Violani, S. Salis, V. Venezia, V. Dolcini, G.Damonte, U. Benatti, P. Carlo, G. Schettini : Pyroglutamate modified amyloid beta-peptide-AbetaN3(pE)-strongly affects cultured neuron and astrocyte survival. J. Neurochemistry, 2002 Sep; 82(6):1480-9. Impact Factor :4,900.
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| Disponibile a:
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Lavorare in Italia dal prossimo marzo 2006 in un laboratorio di ricerca sulla neurodegenerazione.
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| Data ultima modifica :
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10/10/2005 |
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